NAD+

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NAD+ (Nicotinamide Adenine Dinucleotide is a coenzyme naturally present in every cell of the body, critical for energy production, cellular repair, and overall metabolism. It’s not synthesized as a drug but can be supplemented directly or boosted via precursors (e.g., NMN, NR). NAD+ levels decline with age, linking it to aging and age-related diseases, which has sparked interest in its therapeutic use for healthspan and longevity.

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Description

Description

Primary Uses of NAD+

  1. Energy Production:
    • NAD+ is essential for mitochondrial function, converting nutrients into ATP (cellular energy) via the electron transport chain. Supplementation may combat fatigue and boost vitality, especially in aging or chronic illness.
  2. Anti-Aging and Longevity:
    • NAD+ activates sirtuins (e.g., SIRT1), proteins that regulate DNA repair, gene expression, and cellular aging. Raising NAD+ levels is thought to mimic calorie restriction, a known longevity enhancer.
    • It supports PARPs (poly ADP-ribose polymerases), which repair DNA damage, potentially slowing age-related decline.
  3. Cellular Repair:
    • Enhances DNA repair and protects against oxidative stress, which accumulates with age or environmental damage (e.g., UV exposure, pollution).
  4. Neuroprotection:
    • NAD+ supports brain health by maintaining neuronal energy and aiding repair. It’s studied for neurodegenerative diseases like Alzheimer’s, Parkinson’s, and traumatic brain injury, with animal models showing cognitive improvement.
  5. Metabolic Health:
    • Improves insulin sensitivity, fat metabolism, and glucose regulation, making it a candidate for diabetes, obesity, and metabolic syndrome management.
    • Animal studies show it reverses some effects of high-fat diets.
  6. Muscle Function and Recovery:
    • Boosts mitochondrial efficiency in muscles, aiding endurance and repair. Athletes use it to enhance performance and recovery post-exercise.
  7. Cardiovascular Health:
    • Protects blood vessels and heart tissue by reducing inflammation and oxidative stress, potentially lowering risks of atherosclerosis or heart failure.

Additional Potential Uses

  • Addiction Recovery: IV NAD+ therapy is used in some clinics to reduce cravings (e.g., alcohol, opioids) by restoring cellular balance, though evidence is anecdotal.
  • Chronic Fatigue and Fibromyalgia: May alleviate symptoms by improving energy metabolism.
  • Immune Function: Supports immune cell activity, potentially aiding in infection resistance or inflammation control.

How It’s Used

  • Administration:
    • IV Infusions: Direct NAD+ delivery (e.g., 500-1000 mg over hours) for rapid effects, common in wellness clinics.
    • Oral Precursors: NMN (Nicotinamide Mononucleotide) or NR (Nicotinamide Riboside) (250-500 mg/day) are converted into NAD+ by the body—more practical and widely available.
    • Nasal Sprays/Injections: Less common but used for targeted delivery.
  • Dosage:
    • IV: 100-1000 mg per session (1-10 sessions).
    • Precursors: 250-1000 mg/day, depending on product and goal.
    • Dosing varies widely—guided by providers or product labels.

Product Usage: This item is designed exclusively for use as a research chemical in laboratory settings and in vitro experiments, to be handled only by licensed, trained professionals. It is not intended or approved for human or animal consumption. Any misuse, misbranding, or mislabeling as a drug, food, or cosmetic is strictly forbidden. All accompanying information is provided solely for educational purposes.

Additional information

Additional information

Milligrams

100MG

,

200MG