KPV – 5mg
$35.00
KPV is a tripeptide composed of three amino acids: lysine (K), proline (P), and valine (V). It’s a naturally occurring fragment derived from the C-terminal end of alpha-melanocyte-stimulating hormone (α-MSH), a hormone known for its roles in pigmentation, inflammation regulation, and immune modulation. KPV retains many of α-MSH’s beneficial properties, particularly its anti-inflammatory and antimicrobial effects, but in a smaller, more targeted form, making it a promising peptide for various therapeutic applications.
10 in stock
Description
Primary Uses of KPV
- Anti-Inflammatory Effects:
- KPV is renowned for reducing inflammation by interacting with inflammatory pathways inside cells. It inhibits the production of pro-inflammatory cytokines (e.g., TNF-alpha, IL-8) and suppresses pathways like NF-κB and MAPK, which are key drivers of inflammation.
- It’s been studied extensively for inflammatory bowel diseases (IBD) like Crohn’s disease and ulcerative colitis, where it reduces gut inflammation and promotes mucosal healing.
- Gut Health:
- KPV is transported into intestinal cells via the PepT1 transporter, which is upregulated in inflamed colons. This makes it particularly effective for oral administration in treating conditions like ulcerative colitis, irritable bowel syndrome (IBS), and Crohn’s disease.
- Research (e.g., Dalmasso et al., 2008) shows it lowers inflammation in intestinal epithelial and immune cells, offering a natural alternative to steroids.
- Wound Healing:
- KPV accelerates tissue repair and reduces infection risk by combining anti-inflammatory and antimicrobial properties. It’s been shown to improve cosmetic outcomes by minimizing scarring, making it a candidate for post-surgical recovery or chronic wounds.
- Skin Health:
- Applied topically, KPV helps with inflammatory skin conditions like psoriasis, eczema, and acne. It reduces redness, itching, and scaling without the side effects of long-term steroid use, leveraging its ability to calm immune responses in skin cells.
- Antimicrobial Properties:
- KPV exhibits activity against pathogens like Staphylococcus aureus and Candida albicans, supporting its use in fighting infections, particularly in wounds or compromised skin.
- Immune Modulation:
- It balances immune responses, potentially aiding in autoimmune conditions by preventing excessive inflammation while maintaining immune defense.
How It’s Used
- Administration:
- Oral: Capsules or sprays for systemic or gut-specific effects (e.g., 250-500 µg/day).
- Topical: Creams or gels for skin conditions.
- Injectable: Subcutaneous shots for broader anti-inflammatory benefits.
- Iontophoresis: A transdermal method using low-level electric currents to enhance skin penetration.
- Dosage: Varies by purpose—e.g., 200-400 µg/day for injectables, 250 µg twice daily for oral—but should be guided by a healthcare provider.
Product Usage: This item is designed exclusively for use as a research chemical in laboratory settings and in vitro experiments, to be handled only by licensed, trained professionals. It is not intended or approved for human or animal consumption. Any misuse, misbranding, or mislabeling as a drug, food, or cosmetic is strictly forbidden. All accompanying information is provided solely for educational purposes.
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